Figure 4

Rank-order plots comparing (a) COX2 protein expression and (b) phosphorylated EGFR (Y1148) levels. RPMA-generated relative intensity values are plotted for undissected (WhT) and laser capture microdissected tumor epithelium (CE-LCM) for both COX2 expression and phosphorylated EGFR (Y1148) levels. Comparisons are made with three differing levels of starting endogenous tumor epithelium (20, 40 and 60%). Changes in rank ordering are shown with dotted lines connecting the matched patient samples. Quartiles are designated by horizontal lines in each plot.