Figure 4
From: Rhabdoid tumor: gene expression clues to pathogenesis and potential therapeutic targets
Expression of selected genes involved in tumor invasion and metastasis. (a) Pattern of RNA expression of key genes. The expression levels (low to high) are plotted on the y axis. The x axis groups the different tumor types starting with the congenital mesoblastic nephromas (infantile fibrosarcomas) in black, followed by clear cell sarcoma of the kidney in green, rhabdoid tumors in red, and Wilms tumors in blue. (b) Protein expression of SPP1 and PEDF (SERPINF1). The majority of cells within all RT show moderate positivity for SPP1. Note the striking positivity of non-neoplastic renal tubules for SPP1. Clusters of cells within RT show strong positivity for PEDF.
