Figure 2 | Laboratory Investigation

Figure 2

From: Phospholipase Cɛ has a crucial role in ultraviolet B-induced neutrophil-associated skin inflammation by regulating the expression of CXCL1/KC

Figure 2

Comparison of the density of neutrophils in the epidermis of PLCɛ+/+ and PLCɛ−/− mice irradiated with UVB. The shaved dorsal skins of PLCɛ+/+ (white bar) and PLCɛ−/− (black bar) mice were irradiated with a single dose of UVB at 2.5 kJ/m2 (n=10 for each PLCɛ background, 5 male mice and 5 female mice). Skin specimens were prepared at 24 and 48 h after irradiation, and were stained with H&E. The density of neutrophils in the epidermis at each time point was calculated together with samples used in Figure 1 as described in Materials and methods. Data are expressed as mean±s.d. *P<0.05; **P<0.01.

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