Figure 2 | Laboratory Investigation

Figure 2

From: Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma

Figure 2

Expression of hepcidin in HCC. (a, b) Analysis of mRNA by qRT-PCR showed reduced hepcidin expression levels in HCC cell lines (*P<0.05 compared with PHH; PHH=1) (a). Nine analyzed human HCC tissues confirmed the results, expression was lower in the HCC tissues compared with 19 normal liver tissues (*P<0.05; normal liver=1) (b). (c) To determine the hepcidin pro-hormone protein concentration we performed an ELISA assay. Measurement of 16 serum samples of healthy patients compared with 13 serum samples of HCC patients revealed decreased hepcidin levels in HCC patients (*P<0.05).

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