Figure 5 | Laboratory Investigation

Figure 5

From: Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma

Figure 5

HJV as modulator of hepcidin expression. (a) HJV mRNA expression was analyzed in PLC cells transfected with HJV expression construct compared with control transfected cells (pCMX-PL2-Flag). HJV mRNA expression was enhanced in HJV transfected cells compared with control transfected cells. (*P<0.05; control=1). (b) Induction of hepcidin mRNA expression was much stronger in HJV transfected PLC cells after BMP4 stimulation for 20 h compared with control transfected cells after BMP4 stimulation. (*P<0.05 BMP4 treated HJV transfected cells compared with BMP4 treated control transfected cells; control=1).

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