Table 1 Summary of mutant phenotypes at various developmental stages
Stages | No. of mutantsa | Hemorrhages | Cardiac defects | Dead or resorbed* | ||
|---|---|---|---|---|---|---|
Forebrain | Spinal | |||||
Tgfbr2 | E10.5 | 6 (10) | 0 | 0 | 0 | 0 |
E11.5 | 17 (23) | 17 | 0 | 0 | 0 | |
E12.5 | 5 (11) | 5 | 2 | 0 | 0 | |
E13.5 | 7 (9) | 7 | 5 | 0 | 0 | |
E14.5 | 4 (4) | 4 | 4 | 0 | 3 | |
E15.5 | 5 (15) | ND | ND | ND | 5* | |
PN1 | 0 (110) | 0 | 0 | 0 | 0 | |
Alk5 | E10.5 | 8 (10) | 0 | 0 | 0 | 0 |
E11.5 | 12 (14) | 12 | 0 | 0 | 0 | |
E12.5 | 8 (14) | 8 | 5 | 6 | 0 | |
E13.5 | 3 (3) | 3 | 2 | 3 | 2 | |
E14.5 | 3 (5) | ND | ND | ND | 3* | |
E15.5 | 5 (5) | ND | ND | ND | 5* | |
PN1 | 0 (106) | 0 | 0 | 0 | 0 | |
