Table 1 Partial list of Wnt signaling genes with significant expression level changes identified by microarray analysis
From: Wnt activation is implicated in glioblastoma radioresistance
Symbol | Gene | Description | P-value | Fold-change |
---|---|---|---|---|
PRICKLE4 | NM_013397 | Prickle homolog 4 (Drosophila) (PRICKLE4) | 0.018 | 3.66 |
WISP1 | NM_080838 | WNT1-inducible signaling pathway protein 1 (WISP1), transcript variant 2 | 0.046 | 3.64 |
FZD1 | NM_003505 | Frizzled homolog 1 (Drosophila) (FZD1) | 0.014 | 2.62 |
APC | NM_001127511 | Adenomatous polyposis coli (APC), transcript variant 1 | 0.013 | 1.98 |
CITED1 | NM_004143 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | 0.014 | 1.92 |
LEF1 | NM_016269 | Lymphoid enhancer-binding factor 1 (LEF1), transcript variant 1 | 0.031 | 1.77 |
TCF4 | NM_003199 | Transcription factor 4 (TCF4), transcript variant 2 | 0.030 | 1.70 |
PPARD | NM_006238 | Peroxisome proliferator-activated receptor delta | 0.038 | 1.68 |
CTNNBIP1 | NM_020248 | Catenin, beta interacting protein 1 | 0.016 | 1.67 |
NLK | NM_016231 | Nemo-like kinase | 0.019 | 1.56 |
CHD8 | NM_020920 | Chromodomain helicase DNA binding protein 8 | 0.046 | 1.40 |
RUVBL1 | NM_003707 | RuvB-like 1 (E. coli) | 0.003 | −1.29 |
SMAD4 | NM_005359 | SMAD family member 4 (SMAD4) | 0.001 | −1.46 |
PPP2R5C | NM_178587 | Protein phosphatase 2, regulatory subunit B′, gamma isoform | 0.018 | −1.67 |
WNT9B | NM_003396 | Wingless-type MMTV integration site family, member 9B | 0.038 | −1.89 |
AXIN2 | NM_004655 | Axin 2 (AXIN2) | 0.006 | −1.90 |