Figure 1 | Laboratory Investigation

Figure 1

From: Carbon tetrachloride-mediated lipid peroxidation induces early mitochondrial alterations in mouse liver

Figure 1

CCl4-induced liver toxicity 3 or 24 h after administration assessed by (a) ALT and (b) AST levels, (c) H&E staining, (d) TNF-α and (e) Il-6 plasma levels and (f) hepatic DNA integrity on agarose gel. Data are means±s.e.m. for 10–14 mice in each group.*Significantly different from control mice (P<0.05). H&E staining was performed on liver slices and representative photographs of the liver of mice treated for 3 or 24 h with 1 or 1.5 ml/kg CCl4 are shown at × 250 magnification. Arrows indicate inflammatory cell infiltrates. CV, centrilobular vein.

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