Table 2 Caspase activities 3 or 24 h after CCl4-administration

From: Carbon tetrachloride-mediated lipid peroxidation induces early mitochondrial alterations in mouse liver

 

Control +

Control −

C 3 h

CCl4 3 h

C 24 h

CCl4 24 h

Caspase 2

10.66±0.01a

3.98±0.58a,b

1.00±0.17

1.33±0.27

0.89±0.08

0.76±0.17

Caspase 3

37.70±5.38a

1.24±0.27b

1.00±0.05

1.11±0.13

0.61±0.10

0.91±0.07

Caspase 8

1.05±0.10

088±0.07

1.00±0.02

1.13±0.08

0.85±0.02

0.72±0.04

Caspase 9

2.32±0.11a

1.29±0.01b

1.00±0.15

1.05±0.08

0.98±0.05

0.87±0.04

  1. Data are mean±s.e.m. for nine mice per group.
  2. Results are expressed as fold-change of control mice (C 3 h) values.
  3. For negative controls (control−), a specific caspase inhibitor was incubated with the protein extract for 10 min before the reading.
  4. aSignificantly different from control mice (C 3 h) (P<0.05).
  5. bSignificantly different from positive control (control +) (P<0.05).
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