Figure 7

Difference in occurrence of human pathogenic TTR mutations in diverse and uniform amino acid residues in primates. (a) Difference in the ratio of the number of TTR mutations causing various human phenotypes to the number of diverse and uniform TTR amino acid residues. (b) TTR mutations causing different human phenotypes as related to diverse and uniform TTR amino acid residues. Non-amy, nonamyloidogenic. P-values according to Pearson's χ2 test, comparing each group with the other groups. *P<0.05.