Figure 2
From: Metal-free imidazolium salts inhibit the growth of hepatocellular carcinoma in a mouse model
IBN-1 and IBN-9 arrested HCC cells in G1-phase. (a) Treatment of HLE cells with IBN-1 (10 or 100 μM for 24 h) arrested cells in the G1-phase. Notably, the number of cells in the G1-phase increased from 43 to 58%, with a significant concurrent decrease in the number of cells in the S-phase. (b) Treatment of Huh7 cells with IBN-9 (120 μM for 24 h) yielded similar results. All results were expressed as mean±s.e.m. of three experiments. *P<0.05, **P<0.01 and ***P<0.001.
