Figure 1 | Laboratory Investigation

Figure 1

From: Overexpression of ZNF217 in glioblastoma contributes to the maintenance of glioma stem cells regulated by hypoxia-inducible factors

Figure 1

Overexpression and amplification of ZNF217 in GBMs. (a, b) TCGA database analysis demonstrated that the ZNF217 gene is overexpressed in 71.2% (more than twofold increase compared with normal tissues) and amplified in 32% of GBMs. (c) Relationship between amplification and overexpression of ZNF271 in GBMs. ZNF217 amplification is more frequently found in ZNF217-overexpressing GBMs (46.6%) than in non-overexpressing GBMs (16.67%; P<0.001, χ2 analysis). 1–4+ indicate gained copy numbers or increased fold-increase of ZNF217 expression in GBMs compared with normal tissues.

Back to article page