Figure 2

ZNF217 expression in gliomas, as compared with normal brain tissue. (a) qPCR analysis of ZNF217 expression in astrocytomas (A), anaplastic astrocytomas (AA), oligodendrogliomas (O), anaplastic oligodendrogliomas (AO) and GBMs reveals increased expression in all types of gliomas, especially GBMs, compared with normal brain tissue. GBMs expressed significantly higher levels of ZNF217 than normal and low-grade gliomas (A, O and OA; P<0.05). (b, c) Representative RT–PCR and western blots showing ZNF217 is more highly expressed in gliomas than in normal and low-grade glioma tissues. β-Actin and GAPDH were used as loading controls for RT–PCR and western blotting, respectively.