Figure 7 | Laboratory Investigation

Figure 7

From: Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma

Figure 7

Schematic diagram showing the miRNA mediated gene regulations in rhabdomyosarcoma (RMS). PAX3 and CCND2 is regulated by both miR-1 and -206, and miR-29 regulates the expression of CCND2 and E2F7, suggesting a presence of potential miRNA regulatory network that is deregulated in RMS. Previously, we have demonstrated miR-183-mediated regulation of EGR1 in RMS. Downregulated and upregulated miRNAs and their target genes are color coded as green and red, respectively.

Back to article page