Figure 6

Dose-response curves of portal perfusion pressure (expressed as delta change in mm Hg from baseline) to increasing doses of methoxamine (10−6 to 10−4 mol/l) of control rats (●) and rats with steatosis (▴), demonstrating marked hyporesponsiveness in rats with steatosis (*P<0.001 for all doses vs each other within control rats, **P<0.001 for controls vs rats with steatosis at comparative doses).