Table 1 Weight and haemodynamic characteristics of control rats vs rats with steatosis

From: Increased intrahepatic resistance in severe steatosis: endothelial dysfunction, vasoconstrictor overproduction and altered microvascular architecture

 

Controls (n=5)

Steatosis (n=5)

P-value

Body weight (g)

187.0±7.8

131.0±8.9

<0.001*

Liver weight (g)

7.6±0.4

6.61±0.8

0.037*

Liver body weight ratio

0.0406±0.0011

0.0505±0.0054

0.004

MABP (mm Hg)

123.8±4.0

99.4±7.1

<0.001*

PR (bpm)

207.0±35.8

212.0±22.24

0.858

PP (mm Hg)

2.6±0.9

8.8±1.3

<0.001*

CCVP (mm Hg)

0.4±0.5

0.6±0.5

0.580

PCPG (mm Hg)

2.2±1.1

8.2±1.3

<0.001*

  1. Abbreviations: MABP, mean arterial blood pressure; PR, pulse rate; PP, portal pressure; CCVP, caudal caval vein pressure; PCPG, portocaval pressure gradient.
  2. Body weight, liver weight, the ratio between liver and body weight, MABP, PR, PP, CCVP and PCPG are shown for rats receiving the control diet or the methionine–choline-deficient diet for 4 weeks, respectively. The results are expressed as mean±s.d. The P-values of the comparison between rats on the control diet and rats on the MCD diet are listed (independent samples t-test). A P-value <0.05 is considered statistically significant (*).
Back to article page