Figure 1 | Laboratory Investigation

Figure 1

From: Evidence questioning cromolyn’s effectiveness and selectivity as a ‘mast cell stabilizer’ in mice

Figure 1

Effects of cromolyn on PCA reactions in vivo. Female rats (a) or male mice (b–d) injected i.d. with vehicle (saline) or anti-DNP IgE (IgE) were challenged i.v. with DNP-HSA with or without cromolyn (injected simultaneously); we then measured Evans blue extravasation (a, b), ear swelling (c), and leukocyte migration (d). N=4 rats (a), 5 mice (b) and 7–8 mice (c, d) per group from at least two independent experiments. **P<0.01; n.s.: P>0.05.

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