Table 1 Clinicopathological characteristics of melanoma cohorts
Characteristic | Discovery cohort, n=113 | Validation cohort, n=206 |
---|---|---|
Breslow thickness, mm | ||
Mean | 3.08 | 3.45 |
s.d. | 2.25 | 4.61 |
Age at diagnosis, years | ||
Mean | 58.24 | 63.43 |
s.d. | 14.43 | 16.80 |
Sex | ||
Male | 58 (50.5%) | 80 (38.8%) |
Female | 54 (49.5%) | 126 (61.2%) |
Stage at diagnosis | ||
Localized | 89 (82.4%) | 169 (82%) |
Regional | 11 (10.2%) | 33 (16%) |
Distant | 8 (7.4%) | 4 (1.9%) |
Ulceration | ||
Absent | 67 (59.3%) | 67 (52.3%) |
Present | 46 (40.7%) | 61 (47.7%) |
Microsatellites | ||
Absent | 86 (76.1%) | 71 (83.5%) |
Present | 27 (23.9%) | 14 (16.5%) |
Received any therapy | ||
No | 90 (81.1%) | 153 (81.4%) |
Yes | 21 (18.9%) | 35 (18.6%) |