Figure 6
From: Heme oxygenase-1 promotes granuloma development and protects against dissemination of mycobacteria
M. avium CFU counts are higher in lung tissue of infected HO-1 −/− mice as compared with lung tissue form infected HO-1+/+ mice. Mouse lung tissue was homogenized in 2 ml of 7H9 broth medium. Then, 100 μl of 10-fold serial dilutions were plated on 7H10 agar plates and incubated for 10–21 days in 37 °C after which CFUs were counted. CFU counts were significantly higher (*P<0.05) in lung tissue of infected HO-1−/− mice as compared with HO-1+/+ mouse tissue. Values represent the average CFU counts from four mice in either non-infected or M. avium infected groups.
