Table 1 Serum-derived parameters and liver triglycerides of animals fed a standard (SD) or western diet (WD) before PHx (pre-OP) or on postoperative days 1, 2 and 7 (PHx +)
From: Steatosis does not impair liver regeneration after partial hepatectomy
Parameter | Time point | SD | WD | P-valuea |
|---|---|---|---|---|
FFA (nmol) | Pre-OP | 5.3±0.21 | 9.85±0.14 | <0.0001a |
|  | PHx+1 | 9.05±0.66 | 9.26±0.47 | n.s. |
|  | PHx+2 | 8.19±1.16 | 8.81±0.65 | n.s. |
|  | PHx+7 | 8.78±0.64 | 9.04±0.61 | n.s. |
Triglycerides (liver tissue) (μmol/mg) | Pre-OP | 41.27±5.60 | 78.98±8.52 | 0.0008a |
|  | PHx+1 | 32.93±7.09 | 99.27±16.36 | 0.04a |
|  | PHx+2 | 63.17±1.44 | 113.7±18.26 | 0.03a |
|  | PHx+7 | 25.05±11.85 | 103.3±19.52 | 0.03a |
AST (IU/l) | Pre-OP | 26.75±8.0 | 46.25±13.7 | n.s. |
|  | PHx+1 | 4480.0±18 | 2038.0±169.3 | n.s. |
|  | PHx+2 | 113.0±10.54 | 114.7±16.88 | n.s. |
|  | PHx+7 | 68.33±33.22 | 72.83±28.78 | n.s. |
ALT (IU/l) | Pre-OP | 17.5±4.91 | 63.0±29.85 | n.s. |
|  | PHx+1 | 2269.0±389.1 | 1099.0±154.4 | 0.012a |
|  | PHx+2 | 99.33±8.69 | 68.33±9.04 | n.s. |
|  | PHx+7 | 90.0±56.87 | 47.17±31.34 | n.s. |
LDH (IU/l) | Pre-OP | 732.5±201.1 | 2002.0±161.7 | n.s. |
|  | PHx+1 | 30 610.0±3676.0 | 18 201.0±2311.0 | 0.02a |
|  | PHx+2 | 2319.0±559.1 | 1368.0±374.1 | n.s. |
|  | PHx+7 | 2344.0±832.2 | 2578.0±345.4 | n.s. |
T-protein (g/dl) | Pre-OP | 4.13±0.08 | 4.33±0.21 | n.s. |
|  | PHx+1 | 3.73±0.10 | 3.67±0.15 | n.s. |
|  | PHx+2 | 3.03±0.38 | 1.97±0.18 | n.s. |
|  | PHx+7 | 3.73±0.18 | 3.48±1.13 | n.s. |
Albumin (g/dl) | Pre-OP | 2.0±0.06 | 1.33±0.33 | n.s. |
|  | PHx+1 | 1.85±0.09 | 1.92±0.06 | n.s. |
|  | PHx+2 | 1.25±0.25 | 1.0±0.04 | n.s. |
|  | PHx+7 | 2.0±0.06 | 1.67±0.07 | n.s. |
Bilirubin (mg/dl) | Pre-OP | 0.48±0.08 | 0.3±0.04 | n.s. |
|  | PHx+1 | 2.05±0.92 | 2.17±0.82 | n.s. |
|  | PHx+2 | 0.3±0.06 | 0.37±0.08 | n.s. |
|  | PHx+7 | 0.47±0.07 | 0.38±0.03 | n.s. |
Leptin (pg/ml) | Pre-OP | 983.4±170.9 | 36 416.0±21 377.0 | n.s. |
|  | PHx+1 | 5242.0±1042.0 | 17 260.0±2431.0 | 0.01a |
|  | PHx+2 | 1087.0±355.7 | 6717.0±695.4 | 0.002a |
|  | PHx+7 | 975.5±190.1 | 4650.0±412.6 | 0.001a |
Adiponectin (ng/ml) | Pre-OP | 2.72±0.84 | 2.11±1.19 | n.s. |
|  | PHx+1 | 4.06±0.51 | 5.44±0.75 | n.s. |
|  | PHx+2 | 1.98±0.42 | 1.96±0.61 | n.s. |
|  | PHx+7 | 4.27±0.94 | 3.02±0.68 | n.s. |