Figure 3

Representative immunofluorescence images of β1 integrin-deficient and control mouse pancreas at 3 (a) and 7 days (b) post-tamoxifen injection using an anti-β1 integrin antibody. Western blot analyses of β1 integrin-deficient and control mouse β1 integrin expression at 3 (c) and 7 days (d) post-tamoxifen injection (n=4). (e) Pancreas to body weight ratio in β1 integrin-deficient and control mice at 4 and 7 weeks post-injection (n=7–17). (f) Food intake data from 4 weeks post-tamoxifen-injected β1 integrin-deficient mice with respective controls (n=7–8). Data are expressed as means±s.e.m. *P<0.05; ***P<0.001 vs controls. Scale bar=50 μm. Ctrl, control; KO, knockout.