Figure 1 | Laboratory Investigation

Figure 1

From: KCa3.1 channels mediate the increase of cell migration and proliferation by advanced glycation endproducts in cultured rat vascular smooth muscle cells

Figure 1

Effect of AGE-BSA on KCa3.1 currents in cultured rat VSMCs. (a) Membrane currents recorded with the protocol as shown in the inset in cells treated with BSA (200 μg/ml), AGE-BSA (200 μg/ml), and AGE-BSA plus anti-RAGE antibody (5 μg/ml) for 24 h before and after application of TRAM-34 (1 μM). (b) I–V relationships of the mean values of TRAM-34-sensitive current obtained by digital subtraction of the current before TRAM-34 by the current after TRAM-34 application (n=6 for each groups).

Back to article page