Table 1 Physiological data of aging rats

From: Angiostatin production increases in response to decreased nitric oxide in aging rat kidney

Variable

4 Months (n=8)

10 Months (n=8)

16 Months (n=8)

24 Months (n=6)

BW (g)

430±5

632±44a

786±14a,b

820±16a,b,c

SBP (mm Hg)

122±2

119±4

124±3

144±5a,b,c

Cre (mg/dl)

0.22±0.01

0.28±0.01a

0.31±0.03a

0.36±0.02a,b

U-Pro (mg/day)

13±2

44±5a

73±13a,b

331±51a,b,c

  1. Abbreviations: BW, body weight; Cre, serum creatinine; SBP, systolic blood pressure; U-Pro, urinary protein excretion.
  2. Values are expressed as mean±s.e.m.
  3. aP<0.05 versus 4 months.
  4. bP<0.05 versus 10 months.
  5. cP<0.05 versus 16 months.
Back to article page