Figure 1 | Laboratory Investigation

Figure 1

From: Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs

Figure 1

Endometrial cell proliferation in mutant versus wild-type mice synchronized in proestrus. Wild-type and mutant littermates were inoculated with 5 IU of pregnant mare serum gonadotropin (PMSG) and killed 48 h later. BrdU (5-bromo-2′-deoxyuridine) was inoculated 2 h before the mice were killed. Transverse sections of the boundaries between the upper and middle thirds of the uterine horns were stained with anti-BrdU and counterstained with hematoxylin. The areas within the rectangles in panels (a) and (b) are magnified in panels (c) and (d) respectively. The dashed line in panels (a) and (b) demarcates endometrium (inside) from myometrium (outside). Scale bar: 0.5 mm.

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