Figure 2

Micro-computed tomographic (micro-CT) analyses of femora from wild-type and mutant mice. (a) Three dimensional micro-CT images of the trabecular compartment of the distal femur of 6-month-old wild-type and mutant mice with median trabecular thickness. (b) Quantitative analysis of trabecular bone structure using micro-computed three-dimensional images of 11 mutant and 11 wild-type 6-month-old mice. (c) Representative images of left femurs obtained from 6-month-old wild-type and mutant female littermates with median bone values. (d) Quantitative micro-CT analyses of femoral bone lengths in 11 mutant and 11 wild-type 6-month-old mice. In (b) and (d), the error bars represent s.e.