Table 2 Trabecular and cortical bone parameters and length of femora from wild-type and mutant mice

From: Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs

Bone parameter

Wild-type (N=11)

Mutant (N=11)

Increase (%)

P-values

Bone volume/trabecular volume

0.141±0.022

0.190±0.014

34.9

0.094

Trabecular number (per mm)

3.642±0.209

3.976±0.181

9.2

0.25

Trabecular thickness (mm)

0.0572±0.0030

0.0673±0.0014

17.6

0.011

Diaphyseal diameter (mm)

1.316±0.026

1.362±0.015

3.5

0.14

Medullary diameter (mm)

0.785±0.029

0.798±0.018

1.6

0.87

Cortical thickness (mm)

0.260±0.007

0.279±0.011

7.4

0.16

Connectivity density (per mm3)

90.3±10.6

95.6±7.4

5.9

0.53

Length (mm)

15.45±0.21

16.23±0.19

5.0

0.020