Figure 9

The effects of epidermal growth factor receptor (EGFR) and extracellular signal-regulated kinases (ERK)1/2 inhibitors on cytokine-induced changes in total conductance (GT). Dotted line represents total conductance (GT) under basal culture condition (Control). Data reported are representative of the results obtained in four independent experiments and are expressed as mean ± s.e.m.. **P<0.01 and ***P<0.001 versus cells exposed to cytokines in cultures without AG1478 (1 μM) or UO126 (25 μM).