Figure 5

Runx2 silencing impedes thyroid carcinoma cell invasion. (a) Runx2 siRNA cells and control cells are allowed to pass through Matrigel-coated (for invasion) or uncoated (for migration) filters. (b) Runx2 silencing significantly suppresses thyroid carcinoma cell invasion (^*P=0.03), whereas there is no significant effect on cell migration.