Table 2 Runx2 protein expression in various thyroid lesions

From: Transcription factor Runx2 is a regulator of epithelial–mesenchymal transition and invasion in thyroid carcinomas

Histological type

N

Immunopositivity for Runx2

  

Absent

Mild

Moderate

Strong

Normal thyroid

21

15

6

0

0

Graves' thyroid

11

5

4

2

0

Nodular hyperplasia

16

3

11

2

0

Follicular adenoma

19

5

8

4

2

Papillary carcinoma

23

0

0

4

19

Follicular carcinoma

7

0

0

2

5

Undifferentiated carcinoma

10

0

1

5

4

  1. Absent, negative; mild, focal (1 to 9% of cells); moderate, intermediate (10 to 50%); strong, diffuse (more than 50%).
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