Figure 1

Characterization of chondrosarcoma (CS) subtypes. (a) Human and murine BCSCH01 tumors. Human tumor was analyzed in situ by MRI and radiography, and a biopsy was analyzed by hematoxylin/eosin (HE) staining (original magnification × 20). Subcutaneous xenografts in nude mice were analyzed by radiography, HE and Alcian blue staining ( × 20). (b) Human and murine CH56 tumors. The human tumor was analyzed in situ by radiography, and a biopsy was analyzed by HE staining. Paratibial tumors in nude mice were analyzed by radiography, HE, and Alcian blue staining ( × 20). (c,d) Human CH03 and CH34 tumors. The human tumor was analyzed in situ by radiography, and a biopsy was analyzed by HE staining ( × 20 and × 40). St, stroma; Ca, cartilaginous area; DediffT, dedifferentiated tumor; OsM, osseous metaplasia; Bo, bone; arrows, blood vessels.