Table 2 Summary of the genetic characterization of CH03, 34 and 56 cells

From: New chondrosarcoma cell lines and mouse models to study the link between chondrogenesis and chemoresistance

Cell line

BCSCH03

BCSCH34

BCSCH56

Karyotype

Hypertriploidy

Triploidy+translocations

Triploidy+translocations

IDH1

WT

P.R132Ca

WT

IDH2

WT

WT

P. R172S

TP53

c.318delC ; P.Y107TfsX15b

WT

WT

p16INK4A

Deletion

Deletion

Deletion

p14ARF

Normal

Deletion

Deletion

MDM2

Normal

Amplification

Amplification

  1. WT, wild type.
  2. aP. G105G polymorphism.
  3. bP. R72P polymorphism.
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