Figure 5
From: Low doses of Celecoxib attenuate gut barrier failure during experimental peritonitis
Effects of Celecoxib on localization of tight junction (TJ)-associated proteins junction-associated molecule-A (JAM-A) and zonula occludens-1 (ZO-1). (a) JAM-A (red) after injection with normal saline (NS) or LPS, with or without indicated doses (mg/kg) of Celecoxib. (b) JAM-A (red) after sham operation or cecal ligation and puncture (CLP), with or without indicated doses of Celecoxib. (c) ZO-1 (red) after injection with NS or LPS, with or without indicated doses of Celecoxib. (d) ZO-1 (red) after sham operation or CLP, with or without indicated doses of Celecoxib. All images show sections of ileal samples taken 16 h after peritonitis-inducing treatments and are representative of at least three animals in each group. DAPI-stained nuclei appear in blue. Bar=100 μm.
