Table 1 Relative expression levels of selected stemness genes in 12 paired HNSCC cases by Genechip analysis
Symbol | Description | |||||||
|---|---|---|---|---|---|---|---|---|
Max. | Min. | Positive fold-change cases (%) | Mean Ts vs Ns | P-value | Genbank | Systematic | ||
Bmi1 | BMI1 polycomb ring finger oncogene | 3.7 | 0.4 | 7/12 (58%) | 1.22 vs 1.09 | 0.61 | NM_005180 | A_24_P303989 |
HMGA2 | High mobility group AT-hook 2, transcript variant 1 | 297.2 | 0.41 | 11/12 (92%) | 7.79 vs 0.68 | <0.01 | NM_003483 | A_23_P95930 |
GNL3L | Guanine nucleotide-binding protein-like 3 (nucleolar)-like | 6.82 | 1.04 | 12/12 (100%) | 1.23 vs 0.83 | 0.03 | NM_019067 | A_23_P22499 |
CD44 | CD44 molecule (Indian blood group), transcript variant 1 | 4.69 | 0.8 | 10/12 (83%) | 1.30 vs 0.86 | 0.03 | NM_000610 | A_23_P24870 |
YBX1 | Y-box-binding protein 1 | 2.15 | 0.99 | 10/12 (83%) | 1.23 vs 0.90 | <0.01 | NM_004559 | A_32_P218989 |
Epcam | Epithelial cell adhesion molecules | 17.58 | 0.06 | 6/12 (50%) | 3.30 vs 1.38 | 0.29 | NM_002354 | A_23_P91081 |
Prom1 | Prominin 1 (CD133) | 39.31 | 0.08 | 3/12 (25%) | 0.99 vs 1.38 | 0.76 | NM_006017 | A_23_P258463 |
SHH | Sonic hedgehog homolog | 4.65 | 0.11 | 3/12 (25%) | 1.14 vs 1.37 | 0.54 | NM_000193 | A_23_P111657 |
Notch1 | Notch homolog 1, translocation-associated | 2.64 | 0.19 | 4/12 (33%) | 0.97 vs 1.22 | 0.33 | NM_017617 | A_23_P60387 |
