Figure 4 | Laboratory Investigation

Figure 4

From: Activation of platelet-activating factor receptor exacerbates renal inflammation and promotes fibrosis

Figure 4

Pro-fibrotic signaling is downregulated in PAFR KO animals. Gene expression of TGF-β and BMP-7 is shown in (a and b), respectively (*P<0.05 vs WT). In (c), it is shown the ratio TGF-β/BMP-7 (*P<0.05 vs WT). (d) Indicates the protein expression of TGF-β in renal tissue of control animals and WT and PAFR KO mice submitted to UUO (*P<0.05 vs control and PAFR KO groups).

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