Table 2 Ability to detect biliary tree features in mdr2 knockout, bile duct-ligated, and control mice

From: Micro-computed tomography and nuclear magnetic resonance imaging for noninvasive, live-mouse cholangiography

 

microCT

MR

mdr2 knockout mice

 Gallbladder

+

+

 Extrahepatic bile ducts

+/−

+

 Intrahepatic bile ducts

−

+

 Cholelithiasis

−

+

 Ductal strictures

−

+/−

 Ductal dilation

−

+

 Ductal irregularity

−

+

Bile duct ligation mice

 Gallbladder

NA

+

 Extrahepatic bile ducts

NA

+

 Intrahepatic bile ducts

NA

+

 Gallbladder dilation

NA

+

 Ductal dilation

NA

+

Wild-type (control) mice

 Gallbladder

NA

+

 Extrahepatic bile ducts

NA

+

 Intrahepatic bile ducts

NA

+/−

  1. microCT, micro-computerized tomography; MR, nuclear magnetic resonance imaging (any method); NA, not assessed.
  2. −, 0% of mice; +/−, infrequently or inconsistently; +, consistently (>75% of mice).
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