Figure 3 | Laboratory Investigation

Figure 3

From: Primary esophageal and gastro-esophageal junction cancer xenograft models: clinicopathological features and engraftment

Figure 3

The morphologic heterogeneity of the primary tumor is represented in corresponding xenografts. Areas with well/moderate differentiation (a) are acompanied by areas of poorer differentiation as indicated by a less obvious gland formation (b) within the patient tumor. Similarly, the P1 xenograft derived from this patient shows a similar spectrum of differentiation from well/moderate (c) to poor (d) within a single xenograft tumor. (e) and (f) shows this heterogeneity at passage 3.

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