Table 1 Patient characteristics and SYK methylation status

From: Downregulation of spleen tyrosine kinase in hepatocellular carcinoma by promoter CpG island hypermethylation and its potential role in carcinogenesis

 

HCC with SYK methylation (n=36)

HCC without SYK methylation (n=59)

P-value

Age

   

 Median (range) (year)

55 (21–76)

53 (32–73)

0.631

Sex

 Male

26 (72.2%)

50 (84.7%)

0.187

 Female

10 (27.8%)

9 (15.3%)

 

Size

 Median (range) (cm)

6.5 (2.0–14.0)

5.0 (0.5–18.0)

0.533

AJCC stage

 I, II

29 (80.6%)

48 (81.4%)

1.000

 III

7 (19.4%)

11 (8.6%)

 

AFP

 Average (95% CI) (ng/ml)

31 (5–151 000)

153 (5–70 000)

0.738

Background liver

 Chronic hepatitis

8 (22.2%)

23 (39.0%)

0.116

 Cirrhosis

28 (77.8%)

36 (61.0%)

 

Gamma GT

  

0.494

 Average (95% CI) (IU/l)

81.4 (44.9–118.0)

95.8 (71.4–120.2)

 
Back to article page