Table 2 Univariate and multivariate analysis of different prognostic factors for disease-specific survival in 113 patients with NSCLC

From: Overexpression of stathmin 1 is a poor prognostic biomarker in non-small cell lung cancer

 

Univariate analysis

Multivariate analysis

Prognostic factors

HR

95% CI

P-value

HR

95% CI

P-value

Age (≤65/>65 years)

0.812

0.506–1.301

0.386

   

Gender (male/female)

0.703

0.432–1.147

0.158

   

Smoking status (yes/no)

0.724

0.457–1.148

0.170

   

p53 (negative/positive)

0.891

0.519–1.263

0.363

   

Histology (squamous carcinoma/adenocarcinoma)

0.994

0.618–1.598

0.979

   

Differentiation (moderate–well/poor)

2.109

1.282–3.467

0.003*

1.007

0.587–1.728

0.980

Tumor size (≤3/>3 cm)

1.619

0.994–2.637

0.053

   

N stage (N0/N1+N2)

2.154

1.295–3.583

0.003*

1.263

0.717–2.227

0.419

TNM stage (I+II/III)

5.170

3.012–8.873

0.000*

4.326

2.343–7.988

0.000*

STMN1 (high/low)

2.875

1.754–4.712

0.000*

2.247

1.320–3.825

0.003*

  1. Abbreviations: CI, confidence interval; HR, hazard ratio; NSCLC, non-small cell lung cancer; STMN1, stathmin1; TNM, tumor–node–metastasis staging system.
  2. *P<0.05.
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