Table 2 Enrichment analysis of survival-associated proteins
Enrichment category | Enrichment Score | No. of proteins | Gene name | P-value |
|---|---|---|---|---|
Short-term survival associated | ||||
Cytoskeleton | 6.21 | 30 | ALDOA, KRT6C, KRT6A, KRT6B, PDLIM7, PDLIM3, CCT3, VCL, PNN, KRT9, PEA15, CTTN, DES, KRT5, KRT2, TUBB4, H1F0, PPP2R1A, MYO1C, ACTN4, ACTA2, FSCN1, KRT13, FLNC, PALLD, EPB41L2, NME1, CFL1, WDR1, TGFB1I1 | 6.11E-03 |
Ribonucleoprotein complex/protein biosynthesis/RNA processing | 5.85 | 31 | RPL18, RPL13, PABPC4, RPL27A, SYNCRIP, RPS2, PNN, HNRNPL, HNRNPA3, RPL7, HNRNPF, SND1, RPL5, RPL12, PABPC1, ACTN4, RRBP1, PTBP1, EEF2, ILF3, RBMX, HNRNPA1, NCL, RPS8, RPS7, RPL21, RBMXL2, CPSF6, RPS10, SRP72, BAT1 | 3.51E-12 |
Generation of precursor metabolites and energy | 3.86 | 14 | ALDOA, LDHA, ACO1, ADPGK, PGAM1, ATP6V1B2, ATP6V1B1, PPP1CB, PDHB, GAA, ENO2, PDHA1, ATP5A1, ENO1 | 1.83E-04 |
Long-term survival associated | ||||
Copine | 7.16 | 8 | CPNE8, CPNE9, CPNE4, CPNE5, CPNE6, CPNE7, CPNE3, CPNE2 | 4.50E-14 |
Mitochondrion | 2.64 | 19 | CYB5R3, ATP5D, UQCRC1, SLC25A4, SLC25A5, SLC25A6, ETHE1, NDUFA13, PRDX3, IDH3A, SDHA, SLC25A31, ANXA10, PPP2CA, HEBP1, HARS2, COX6B1, ATP5H, MDH2 | 4.67E-03 |
Generation of precursor metabolites and energy | 2.33 | 10 | SDHA, ATP5D, UQCRC1, SLC25A4, NDUFA13, ERO1L, ATP5H, IDH3A, MDH2, MDH1 | 7.79E-04 |
