Table 3 Multivariate COX regression analysis evaluating PRELP and RPS8 staining with PDAC survival

From: Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma

Variable

P-value

HR

95% CI, lower

95% CI, upper

A. PRELP bottom tertile staining in multivariate analysis

 High grade

0.039

1.511

1.022

2.235

 pN1

0.012

1.632

1.116

2.388

 BottomTertile_PRELP

0.062

0.684

0.459

1.019

B. RPS8 top quartile staining in multivariate analysis

 Female

0.081

1.398

0.96

2.037

 High grade

0.003

1.788

1.217

2.627

 pN1

0.026

1.546

1.053

2.272

 TopQuartile_RPS8

0.012

1.806

1.139

2.863

C. Combination of ‘Low-RPS8 and High-PRELP’ vs all others

 Female

0.074

1.407

0.967

2.049

 High grade

0.035

1.521

1.03

2.247

 pN1

0.024

1.555

1.059

2.283

 LowRPS8_HighPRELP

0.024

0.638

0.432

0.942

D. Combination of ‘High-RPS8 and Low-PRELP’ vs all others

 High grade

0.008

1.686

1.146

2.481

 pN1

0.009

1.682

1.136

2.49

 HighRPS8_LowPRELP

0.001

2.685

1.464

4.924