Figure 2 | Laboratory Investigation

Figure 2

From: Development of non-traumatic osteonecrosis of the femoral head requires toll-like receptor 7 and 9 stimulations and is boosted by repression on nuclear factor kappa B in rats

Figure 2

Histological appearance of the femoral head affected by osteonecrosis. Panels show hematoxylin and eosin-stained femurs. Typical images from the Imiquimod+Saline group with ONFH (a) and without ONFH (b) are shown. The diffuse presence of empty lacunae and pyknotic osteocytic nuclei in the bone trabeculae accompanied by bone marrow cell necrosis was also observed in the femoral head of rats with ONFH (a). Scale bar: 100 μm.

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