Figure 3 | Laboratory Investigation

Figure 3

From: Development of non-traumatic osteonecrosis of the femoral head requires toll-like receptor 7 and 9 stimulations and is boosted by repression on nuclear factor kappa B in rats

Figure 3

Activity of transcription factors. (a) EMSA for NF-κB and IRF7 in Imiquimod+Saline and Imiquimod+MPSL rats on Day 1. Lane 1 contains no extract. Lane 2 contains extract from untreated rat. Lane 3 contains extract from rat treated with Imiquimod+Saline. Lane 4 contains extract from rat treated with Imiquimod+MPSL. (b) Activity of NF-κB and IRF7. A repression in NF-κB activity was observed at Day 1 after corticosteroid treatment. Data represent the mean±s.e.m. **P<0.01 compared with Imiquimod+Saline rats.

Back to article page