Figure 3

Effects of DAPT on Treg cells. Cells from ITP patients and healthy controls were treated with various concentrations of DAPT ranging from 2.5 to 20 μ M for 72 h, and then Treg cells were analyzed by FACS. (a) Lymphocytes. (b) CD4⁺ T lymphocytes. (c) Representative scattergrams of intracellular expression of Foxp3 on CD4⁺CD25⁺ T cells in all treatments in ITP patients and healthy controls. (d) The comparison of Treg cells between ITP patients and healthy controls without DAPT treatment. (e) The proportion of Treg cells from ITP patients and healthy controls after DAPT treatment. Data are shown as median (range). *P<0.05.