Table 2 Correlation between ITGB4 expression and clinicopathological factors
Factors | Total, n (%) | ITGB4 expression, n (%) | P-value | |
|---|---|---|---|---|
Low | High | |||
Age (years) | 0.072 | |||
<60 | 33 (25) | 20 (15) | 13 (10) | |
≥60 | 101 (75) | 43 (32) | 58 (43) | |
Gender | 0.147 | |||
Male | 85 (63) | 44 (33) | 41 (31) | |
Female | 49 (37) | 19 (14) | 30 (22) | |
Tumor size | 0.327 | |||
<3 cm | 77 (57) | 39 (29) | 38 (28) | |
≥3 cm | 57 (43) | 24 (18) | 33 (25) | |
Tumor location | 0.499 | |||
Pancreas head | 89 (66) | 40 (30) | 49 (37) | |
Body and tail | 45 (37) | 23 (17) | 22 (16) | |
Grade | < 0.001b | |||
1/2 | 100 (75) | 58 (43) | 42 (31) | |
3 | 34 (25) | 5 (4) | 29 (22) | |
Lymphatic invasion | 1.000a | |||
Absent | 4 (3) | 2 (1) | 2 (1) | |
Present | 130 (97) | 61 (46) | 69 (52) | |
Neural invasion | 0.051a | |||
Absent | 7 (5) | 6 (4) | 1 (1) | |
Present | 127 (95) | 57 (43) | 70 (52) | |
Major vessel involvement | 0.464 | |||
Negative | 85 (63) | 42 (31) | 43 (32) | |
Positive | 49 (37) | 21 (16) | 28 (21) | |
Margin status | 0.815 | |||
Negative | 97 (72) | 45 (34) | 52 (39) | |
Positive | 37 (28) | 18 (13) | 19 (14) | |
Lymph node metastasis | 0.022b | |||
Negative | 27 (20) | 18 (13) | 9 (7) | |
Positive | 107 (80) | 45 (34) | 62 (46) | |
UICC stage | NA | |||
IA | 3 (2) | 1 (1) | 2 (1) | |
IB | 2 (1) | 1 (1) | 1 (1) | |
IIA | 22 (16) | 16 (12) | 6 (4) | |
IIB | 104 (78) | 44 (33) | 60 (45) | |
III | 2 (1) | 1 (1) | 1 (1) | |
IV | 1 (1) | 0 (0) | 1 (1) | |
