Table 2 Clinical and functional characteristics of the population studied

From: LL-37 secreted by epithelium promotes fibroblast collagen production: a potential mechanism of small airway remodeling in chronic obstructive pulmonary disease

 

Non-smokers

Smokers

Smokers with COPD

Subjects (n)

20

22

18

Age (years)

54 (11)

57 (10)

59 (9)

Sex (female/male)

4/16

1/21

0/18

Smoking history (pack-years)

0

25 (13)

39 (27)

FEV1 (% predicted)

95 (14)

99 (10)

69 (17)a,b

FEV1/FVC %

85 (9)

79 (6)

61 (6)a,b

GOLD stage

 1

—

—

0

 2

—

—

14

 3

—

—

4

 4

—

—

0

  1. Abbreviations: COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in one second; FVC, forced vital capacity.
  2. Data are expressed as mean (s.d.).
  3. aP<0.01 vs non-smokers.
  4. bP<0.01 vs smokers without COPD.
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