Figure 1

Histopathological and immunohistochemical findings of HP-induced gastritis in WT and OPN KO mice. (a) Assessment for bacterial colonization in HP-infected stomach tissues. (b) Histopathological scoring for gastritis. Results are presented as mean±s.e.m. (n=10). (c) Representative H&E images of gastric tissues at both 8 and 16 weeks after infection. (d) Quantitation of F4/80, CD3-positive cells, and polymorphonuclear cells at 8 and 16 weeks after infection. Results are presented as mean±s.e.m. (n=10). (e) Representative immunohistochemical images of inflammatory cells infiltrated in stomach tissues. P-values <0.05 are designated with asterisks.