Figure 1 | Laboratory Investigation

Figure 1

From: Vascular endothelial growth factor receptor-3 is a novel target to improve net ultrafiltration in methylglyoxal-induced peritoneal injury

Figure 1Figure 1

LYVE-1-positive lymphatic vessels were increased and dilated in the diaphragm of methylglyoxal mouse models compared with controls. Expression of lymphatic vessels was predominant in the diaphragm compared with that of control mice. Quantification of immunohistochemical parameters indicated the following: (a) LYVE-1-positive lymphatic vessels were significantly increased in the diaphragm, but not in the parietal peritoneal membrane; CD31-positive vessels (b), expression of type III collagen (c), and CD68-positive macrophages (d) were significantly increased in the diaphragm of methylglyoxal model mice compared with normal control mice. (each group, n=6). Scale bars, 100 μm. LYVE-1, lymphatic vessel endothelial hyaluronan receptor-1; NS, not significant.

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