Figure 5 | Laboratory Investigation

Figure 5

From: The receptor for advanced glycation end products impairs collateral formation in both diabetic and non-diabetic mice

Figure 5

WT diabetic mice have impaired function but RAGE KO diabetic mice are not statistically different. The recovered function in the leg following HLI was assessed by monitoring the distance run on a wheel in 7 days. The total distance is plotted as mean and s.e.m. The WT+DM mice ran significantly less than the Sham group, while all the other groups were not significantly different than each other (*P=0.0087 and n=3–6). KO, knockout; RAGE, receptor for advanced glycation end products; WT, wild type; WT+DM, wild-type mice with diabetes.

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