Figure 6 | Laboratory Investigation

Figure 6

From: Reversal of maladaptive fibrosis and compromised ventricular function in the pressure overloaded heart by a caveolin-1 surrogate peptide

Figure 6

CSD inhibits eNOS activation. Mice were treated as described in the Methods. For Sham control, samples from 6 weeks after surgery were used. LV tissue was extracted with RIPA buffer and the resulting soluble fraction used in Western blotting experiments using antibodies against phospho-eNOS-S1177 and total eNOS. Thin arrow indicates the position of dimeric eNOS (280 kDa), open arrow indicates monomeric eNOS (140 kDa). Similar results were obtained in independent experiments.

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