Figure 3 | Laboratory Investigation

Figure 3

From: DA-1229, a dipeptidyl peptidase IV inhibitor, protects against renal injury by preventing podocyte damage in an animal model of progressive renal injury

Figure 3

Effects of DA-1229 on profibrotic and proinflammatory molecules in renal cortical tissue. (a) Glomerular mesangial expansion scores and immunostaining scores. (b) Effect of DA-1229 on macrophage infiltration. (c) mRNA expression in renal cortical tissue. (d) Representative western blot showing expression of the GLP-1 receptor, ABCA1 and HMG-CoA reductase in renal cortical tissue. Values are expressed as means±s.e.m. *P<0.05, ***P<0.001 vs db/m group; #P<0.05, ##P<0.01, ###P<0.001 vs db/db group.

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